The aim of the research was to study the psychological status of young men of military age with hypertension (AH) and to identify relationships with clinical data and the results of 24-hour blood pressure monitoring (DBPM).
Materials and methods: 181 young men aged 18 to 27 years inclusive (average 21.3±0.2 years) with a confirmed diagnosis of primary AH were examined. Comprehensive psychological testing was carried out among 26 volunteers using questionnaires recommended by the Ministry of Defense of the Russian Federation for psychological testing of persons called up for military service (Khanin-Spielberg scale (situational (ST) and personal anxiety (LT), “Prognosis” scale (nervous-psychic resistance (NPR), PSM-25 (experience of stress) and the HADS scale (anxiety and depression), studied the relationship between test results among themselves and with DBPM parameters, the value of the level of statistical significance was taken equal to 0.05.
Results. A simple interpretation of a complex of psychological tests showed the psychological well-being of the examined hypertensive individuals. A correlation analysis of scores scored on various psychological scales among themselves confirmed the validity and informativeness of the selected methods. A statistically significant moderate negative correlation was found between the number of points assessing the NS of an individual with the duration of AH, estimated in years, which indicates the protective nature of psychological discharge in relation to AH. Thus, our data showed that NS is the main psychological resource of conscripts and determines the development of AH among military personnel. As one of the methods of safe psychological relaxation, the method of serial drawing was proposed (Sysoeva, Korneeva, 2018).
In addition, moderate positive correlations were found between the scores scored on the scales assessing the experience of stress (PSM-25) and the level of depression (HADS) with the average daily and daily DBP values and the average daily heart rate.
Conclusions. 1. Among the persons of military age with primary hypertension, there was revealed the predominance of low levels of situational, personal anxiety and stress, normal indicators of anxiety and depression, a high degree of neuropsychic stability, which negatively correlated with the duration of hypertensive anamnesis. 2. The results of psychological tests positively correlate with the DBPM parameters that characterize DBP, which allows us to consider the methods of psychological correction among young men of military age as additional non-drug measures.

From the start of the new coronavirus pandemic there remains the question about its effects on the psyche of people. Judging from the earlier cases of similar illnesses like MERS or TOPC, some researchers assume that the new coronavirus infection can lead to a harsher or worser course of many mental illnesses. With the goal of finding those patterns we conducted a survey of people who were infected with the new strain of the coronavirus infection of different levels in the Republic of Sakha (Yakutia). The survey covered 82 respondents of different age groups (from 18 to 30 years old – 43 people, from 31 to 44 years old – 13 people, from 45 to 59 – 21 people, from 60 to 74 – 5 people), with 69 individuals being female (84.2 %) and 13 individuals being male (15.8 %). The average age of the respondents was 34.5 years. Out of all the respondents, 23 (28 %) people received the treatment in hospital, 59 (72 %) people were treated in ambulatory conditions. The survey was based on the hospital anxiety and depression scale (HADS). This scale consists out of two parts and 14 questions, with each part including 7 questions. For the study, the hospital anxiety and depression scale (HADS) was duplicated, which means it had variations to assess how the respondents feel before and after being infected with the new strain of the coronavirus. The results of the survey of those people that had the new coronavirus infection and were graded by the HADS, the signs of clinical depression were seen in 2.4 % of the respondents before being infected with the new strain of coronavirus; after being cured this group of respondents increased to 14.7 %. Before the illness, signs of clinical depression were manifested in 1.2 % of the respondents; after the illness this number grew to 6.1 %. The signs of needed clinical anxiety were shown by 6 respondents (7.3 %); clinical depression was diagnosed in 14 respondents (17.1 %). An increase state of anxiety was found in the elderly (3.6 %) and states of depression in the young (17 %).

Retention of the third lower molars is quite common. Surgery for this pathology is one of the most complicated in ambulatory surgical dentistry and is often accompanied by inflammatory complications. The antiinflammatory drug therapy is used to stop the inflammatory process in the retromolar area, in combination with the pocket rinsing under the operculum with solutions of antiseptics, antibacterial drugs and physiotherapy, as well as the sorbent SUMS-1.
The authors proposed an effective method of correction of vestibular and lingual tilt of the lower third molars, allowing them to be preserved. A three-part incision is made on the side of the third molar dystopia under local anesthesia on the background of premedication After acute inflammatory phenomena in the area of an erupting tooth subside,. Then the mucosal-periosteal flap is peeled off from the vestibular and lingual sides of the jaw and the compact plate is perforated with a round bur in a staggered pattern, without penetrating into the cancellous bone substance. The compact plate is perforated only in the area of the root apex of the dystopian tooth on the inclined side; the perforations are made in the projection of the tooth root along its entire length on the opposite side of the inclined tooth. The number of holes depends on the degree of inclination of the tooth and the direction of movement. The operating wound is washed with a suspension of the sorbent SUMC-1 in physiological solution of sodium chloride in a ratio of 1:2 after the weakening of the bone tissue. The mucosal-periosteal flap is put on the place and the wound is sutured. After 1-2 days, orthodontic correction of the wisdom tooth position is started. The patient undergoes a selective cusps grinding of the upper and lower eighth teeth and further prescribes mechanotherapy, which consists in pressing on the tooth with the tip of the tongue or finger pressure on the tooth depending on the direction of the inclination.
The original method developed for the correction of the abnormal position of the lower wisdom teeth expands the possibilities of preservation and reduces the incidence of inflammatory complications during their difficult eruption.

Study Objective: to determine the mercury content in the body of children as well as in soil and river fish to assess the level of risk of adverse effects on a human body.
Study Design: analytical observational, cross-sectional study.
Materials and Methods. A quantitative analysis of mercury in hair of conditionally healthy children (n=62), the upper layer of soil (n=15) taken on the territory of the former cellulose and cardboard manufacturing plant (CCMP) located in one of the cities of the Khabarovsk region and in fish (n=27) living in the Amur river downstream was performed using inductively coupled plasma mass spectrometry. The relationship between the level of mercury and cognitive abilities of adolescents was studied.
Study Results. An average content of mercury in the upper layer of the soil was 0.85 mg/kg; with the maximum value of the mass fraction of mercury 1.25 mg/kg, the mercury concentration was 8.5-12.5 times higher than the Russian background value. When determining the concentration of mercury in the fish muscle tissue – the main source of organic mercury for children, it was revealed that the content of mercury in the tissues of predatory fish ranged from 0.47-0.52 mg/kg, while the mercury level in non-predatory fish was 0.24 mg/kg. The average mercury content in hair of adolescence was 0.47±0.05 mg/kg and 0.19±0.02 mg/kg in 6-7-year-old children, and it did not exceed the critical level.
Conclusion. It was found out that the content of mercury in the soil had significantly decreased compared to 2009, but the level remains above the Russian background value. Mercury content in part of the fish muscle living in the Amur River downstream was higher in predatory species. The concentration of mercury in the children organism permanently living on the territory of anthropogenic pollution did not exceed the threshold level, but the detected background values may have contributed to concentration decrease.

Healthy lifestyle and its advertising play an important role in ensuring demographic growth and strengthening the health of the Russian population. Attempts are being made to apply it, but in terms of their content, scope and systematic nature, they often do not correspond to the possibilities of advertising a healthy lifestyle. The means of modern promotion of a healthy lifestyle are outdoor advertising, television, radio and social advertising in print media, social films, educational programs. Social advertising is a type of communication, the purpose of which is to draw attention to the current problems of society and its moral values. The article discusses the importance of social advertising on a healthy lifestyle of students of the Institute of Medicine, M. K. Ammosov North-Eastern Federal University. An anonymous survey was conducted in the form of a questionnaire for 30 respondents. The fundamental principles of the formation of a healthy lifestyle among students, which makes it possible to preserve and strengthen health, were studied; the peculiarities of the influence of social advertising on the preservation and development of students’ health and the formation of a healthy lifestyle among them were highlighted; a number of measures to improve the quality of social advertising for the formation of a healthy lifestyle among students were proposed.

The ultra-low birth rate in modern society is the leading cause of depopulation. Changing the standard of youth sexual behavior should be regarded as one of the main ways to preserve the reproductive potential and social stability of the state. The development of methods of preventive work on the formation of health-saving behavior in the reproductive sphere in most works concerns girls. The absence of a socio-hygienic model for the formation of health-saving behavior in the reproductive sphere among young men was the rationale for the development of such a model by the specialists of the children’s polyclinic.
The purpose of this work was to present the experience of developing and implementing a socio-hygienic medical-organizational technology for the formation of health protection in young men in the reproductive sphere.
Results. The rationale for the development of a socio-hygienic model was the results of a preliminary medical and sociological study – a survey of young men and their parents: a high proportion of sexually active young men with an early sexual debut, using unprotected intercourse, the prevalence of promiscuity against the background of a low level of knowledge about reproductive health, motivation for health protection in the reproductive sphere and the insufficient role of the family in the issues of sexual education of adolescents; a high level of agreement among the parents of young men about the need to involve competent specialists, doctors and psychologists, in the systematic and planned work on the sexual education of their sons. The social and hygienic model was developed on the basis of an interdepartmental and interprofessional approach with the participation of children’s polyclinic doctors, teachers, psychologists and social workers. Structurally and functionally, the model corresponds to the educational cluster, assumes a stage-by-stage implementation of activities, and includes as the main component the innovative educational program “Young Gentleman’s School” within the framework of the School of Reproductive Health for Boys, implemented on the basis of secondary schools territorially attached to the children’s polyclinic. Participation in the program of the School of Reproductive Health for Boys during one academic year was accompanied by an increase in the level of knowledge about reproductive health and a ranked level of motivation of adolescents to preserve health in the reproductive sphere, a smaller increase in the proportion of sexually active boys and a relative increase in those who use protected sexual intercourse among them.
Conclusion. The development and implementation of a social and hygienic model for the formation of health savings in the reproductive sphere among young men and the implementation of the innovative educational program “Young Gentleman’s School” are medical and organizational technology for managing health savings in this area. Increasing the level of motivation of young men to preserve reproductive health through obtaining reliable and complete information from competent specialists – a pediatric urologist-andrologist and a psychologist, contributes to the formation of health-saving sexual behavior.

The article analyzes the results of studies of the compensatory-adaptive and reserve capabilities of the body in representatives of the Asian populations of Yakuts and Central Asia in the extreme conditions of Yakutia. It is commonly known that Yakutia is characterized by a sharply continental climate, which causes adaptive changes in the basic systems of the body. Anthropometric indicators were studied, such as body length, weight, waist circumference, hips circumference, the state of the cardiovascular system in terms of average blood pressure, heart rate and body mass index. To assess the compensatory-adaptive capabilities of the body, the Kerdo index was calculated to assess the state of autonomic regulation based on the values of pulse and diastolic pressure according to the formula, the index of functional changes according to the method of R. M. Baevsky et al. (1979) in points, which shows the degree of adaptability of the body, the state of functional reserves and can serve as a kind of prognosis of health.
Statistical processing of the material was carried out using the IBM SPSS STATISTICS 21.0 software package. To assess the relationship between the studied parameters, a non-parametric correlation analysis according to Spearman and Pearson was carried out. The study revealed that a greater number of overweight and obese individuals were found among the indigenous population compared with natives of the southern regions. The average waist circumference was also statistically significantly higher among the indigenous group. The study of the main parameters of the cardiovascular system showed that they allow us to identify the spectrum of adaptive and adaptive reactions of the body and have ethnic characteristics. Shifts in body mass index can be considered as one of the options for the violation of compensatory-adaptive mechanisms.

The placenta is a fetal organ providing the interchange between mother and fetus. An important role in the regulation of local hemostasis belongs to the so-called brush border of syncytiotrophoblast villi, which is directly washed by maternal blood. Microvilli secrete placental alkaline phosphatase, which is a marker of transport processes and activates enzymes for many metabolic processes, participates in cell proliferation and tissue differentiation, carries out IgG transport to the fetus.
The purpose of the work is to characterize the development of syncytiotrophoblast of the epithelium of the placenta villi at different dates of gestation during physiological pregnancy. To achieve the goal of the study, the tasks were set:
1. Study the dynamics of villi branching and the structure of the trophoblastic epithelium of villi from the stage of branched chorion to the end of pregnancy.
2. Determine the area of the trophoblastic epithelium of villi and study the immunohistochemical features of its main components using antibodies placental alkaline phosphatase, β – chorionic gonadotropin. 3. Study the dynamics of structural transformations and secretory activity of cyto- and syncytiotrophoblast at different gestational dates.
Morphogenesis of syncytiotrophoblast of villous epithelium has been studied using histological, immunohistochemical and morphometric studies.
The morphology of microvilli has been traced throughout the gestation period. The first forming microvilli were detected by 5 weeks; by 7 weeks, they were taller and flask-shaped; 8 weeks – had a branching structure; 9 weeks – non-branching structure, large and cylindrical; by the end of pregnancy (39-40 weeks) – rare, and there were no microvilli in the area of syncytio-capillary membranes.
At 4-5 weeks, there is a weak degree of immunoexpression of β-hCG in the invasive cytotrophoblast and cytotrophoblastic epithelium and negative with the antibody against placental alkaline phosphatase. The area of the epithelium is 4,863.2 μm². At 6-7 weeks, the mean area of the villi is 19,705,5 μm². At 8-10 weeks, maximum epithelial area (6,370,7 μm²) and onset of placental alkaline phosphatase immunoexpression in the brush border area. In the period of 18-24 weeks, the area of villi decreases to 3,285,9 μm². At 39-40 weeks, terminal villi dominate with minimal values of the area of the trophoblastic epithelium, which is 786,2 μm². Syncytiocapillary membranes appear. A pronounced two-layer immunoexpression of placental alkaline phosphatase in the epithelium of all types of villi remains.

Diabetes mellitus (DM) is a complex, multifactorial metabolic disease that tends to steadily increase and affects the quality and life expectancy of the population. Cardiovascular complications accompanying this endocrine pathology most often lead to early disability and are the cause of death of patients. The main role in the pathogenesis of diabetic angiopathies belongs to the manifestation of free radical oxidation (SRO). Based on this premise, the purpose of our study was to study the effectiveness of taking an antioxidant (AO) of plant origin – dihydroquercetin (DHA) in the conditions of complex therapy of patients with type 2 diabetes living in the northern region. 132 people were examined, of which 78 patients with type 2 diabetes were included in the main group, 54 representatives of the alien population of the Khanty-Mansi Autonomous Okrug – Yugra were included in the control group (conditionally healthy, without metabolic disorders). The content of lipid peroxidation products in the blood of all the examined persons was determined

This paper presents a definition of the variability of morphometric parameters of first and second year students of three major universities of the city of Krasnoyarsk, depending on the type of constitution. The study of somatometric indicators is important for determining physical development and general health. The study covered 765 students aged 18 to 20 years (393 girls and 372 boys). Somatometry was carried out according to V.V. Bunak’s methodology, adopted at the Moscow State University Research Institute of Anthropology in the morning with a standard set of tools. The following anthropometric parameters were measured: body length, body weight, girth, anterior-posterior and transverse diameters of the chest. The type of constitution was determined using the Ries-Eysenck index. The hand strength of the right and left hands was measured using a medical electronic manual dynamometer DMER-120-0.5, as well as the index of hand strength as a percentage. In females, the predominant type of constitution according to the Ries-Eysenck index was asthenic, with 57.0 %; in males, the normosthenic type dominated at 45.5 %. The gender heterochrony of the values of the median anthropometric indicators in adolescence, depending on the somatotype, was revealed. Morphometric parameters of body length, girth, transverse and antero-posterior chest diameters, and absolute indicators of carpal dynamometry gradually increase from asthenic to picnical type of constitution, both in boys and girls. The body length is maximal in asthenic somatotype in all subjects. The index of wrist strength is maximum in girls of the asthenic type of constitution and in boys of the normosthenic type, the minimum is in all students of the picnical somatotype. The correlation of absolute values of dynamometry and body weight was determined in all subjects. A moderately pronounced positive relationship was revealed between the values of the index of the wrist strength of the right hand and the chest girth, while the Spearman index in girls is 0.4 (p<0.05), in boys – 0.39 (p<0.05).

In lymphology, there is a great potential of knowledge about the role of the lymphatic system in the implementation of water homeostasis, as one of the most important factors of the constancy of the internal environment of the body, drainage, and detoxification of tissue fluid and lymph. The lymphatic system is one of the first to react to the inflammatory process in any region of the human body; therefore, an obligatory element of the standard of examination of patients is to assess the condition of regional lymph nodes. At the same time, the lack of data on the involvement of the lymphatic system in the development of exudative otitis media hinders the development of new pathogenetically sound modern methods of lymphotropic therapy of one of the diseases common in otorhinolaryngology. In this work, the features of structural transformations of different groups of neck lymph nodes (superficial, facial, deep) belonging to the lymphatic region of the middle ear are studied and shown under physiological conditions, when modeling exudative otitis media and after lymphotropic therapy involving the introduction of a mixture of drugs into tissues using low-frequency ultrasound. According to the degree and nature of the response of the structural components of the nodes to the modeling process in the experiment of exudative inflammation in the middle ear and therapeutic measures aimed at lymphosanation, nodes of the first order – deep lymph nodes, and of the second order – superficial lymph nodes were identified. Therapy aimed at the rehabilitation of the lymphatic region of the middle ear and associated cavities leads to complete normalization of the lymph nodes and relief of inflammatory processes, therefore it can be considered pathogenetically justified.