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REPERFUSION SYNDROME IN ENDOVASCULAR MYOCARDIAL REVASCULARIZATION: A CLINICAL OBSERVATION

https://doi.org/10.25587/SVFU.2023.30.1.004

Abstract

CHD retains a leading position worldwide due to high rates of mortality and disability. The best and proven strategy aimed at saving the damaged myocardium in ST-segment elevation myocardial infarction (STEMI) is rapid and effective reperfusion of the ischemic heart muscle through primary percutaneous coronary intervention (PCI) or pharmacoinvasive therapy. However, the restoration of blood flow by itself can lead to reperfusion damage to the affected myocardium. In acute coronary catastrophe caused by acute occlusion of the coronary artery, myocardial stun and hibernation develop locally. With STEMI, hibernation can be observed both near the infarction zone and in more distant areas of the myocardium. In patients with STEMI, the appearance of life-threatening arrhythmias (ventricular tachycardia and ventricular fibrillation) occurs in 4.3 % of cases and is primarily associated with reperfusion after PCI. In most cases, arrhythmias that occur during the procedure are stopped spontaneously; however, when accompanied by ventricular tachyarrhythmia, hemodynamic instability, the use of electric pulse therapy (EIT) is provided. The article presents a clinical case of a patient C., 52, whose reperfusion syndrome manifested itself by the development of life-threatening ventricular tachyarrhythmias: unstable ventricular tachycardia «torsade de points» with transformation into VF, which were stopped by EIT: defibrillation. No recurrence of ventricular tachyarrhythmia was observed in this patient. At this stage, we explain the resulting episode of unstable ventricular tachycardia with short-term myocardial stunning due to short-term ischemia and myocardial damage.

About the Authors

A. M. Palshina
Ammosov North-Eastern Federal University
Russian Federation

PALSHINA Aida Mikhailovna – Candidate of Medical Sciences, Associate Professor, Department of Hospital
Therapy, Occupational Diseases and Clinical Pharmacology, Institute of Medicine

677000, Yakutsk, ul. Oyunskogo, 27

phone: 8(914)226-59-39



N. N. Gryaznukhina
Ammosov North-Eastern Federal University
Russian Federation

GRYAZNUKHINA Natalia Nikolaevna – Candidate of Medical Sciences, Associate Professor, Department
of Hospital Therapy, Occupational Pathology, Clinical Pharmacology, Institute of Medicine

677000, Yakutsk, ul. Oyunskogo, 27

phone: 8(929)648-81-67



P. E. Barashkov
Ammosov North-Eastern Federal University
Russian Federation

BARASHKOV Petr Egorovich – student, Institute of Medicine

677008, Yakutsk, Sergelyakhskoe shosse 4 km, 13

phone: 8(964)4227056



V. A. Ananieva
Ammosov North-Eastern Federal University
Russian Federation

ANANYEVA Victoria Anatolyevna – student, Institute of Medicine

677010, Yakutsk, ul. Ya. Potapova, 19/1, apt. 31

phone: 8(964)4227056



N. N. Silina
Sakha Republic (Yakutia) Hospital № 1 – National Center of Medicine
Russian Federation

SILINA Natalya Nikolaevna – Head, Department of Cardiology with Intensive Care for Patients with Acute
Coronary Syndrome

677027, Yakutsk, ul. Ordzhonikidze, 46/1, apt. 29

phone: 8(964)4235888



L. K. Sosin
Sakha Republic (Yakutia) Hospital № 1 – National Center of Medicine
Russian Federation

SOSIN Leonid Konstantinovich – X-ray surgeon, Department of Radiation Diagnostics

677010, Yakutsk, Sergelyakhskoe shosse, 4

Phone: 8(914)8227938



D. A. Pavlov
Sakha Republic (Yakutia) Hospital № 1 – National Center of Medicine
Russian Federation

PAVLOV Dmitry Anatolyevich – anesthesiologist-resuscitator, Intensive care Unit

677001, Yakutsk, ul. P. Osipenko, 5B, building 1, apt. 169

Phone: 8(962)7367020



References

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4. Clinical recommendations “Acute myocardial infarction with ST segment elevation electrocardiogram”, 2020: https://cardioweb.ru/files/glavny-kardiolog/rekomendation

5. I.E. Vereshchagin, R.S. Tarasov, E.I. Vereshchagin, V.I. Ganyukov “Methods of cardioprotection in myocardial infarction. The current state of the issue”: https://cyberleninka.ru/article/n/metody-kardioprotektsiipri-infarkte-miokarda-sovremennoe-sostoyanie-voprosa

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7. ESC/EACTS Recommendations on Myocardial revascularization, 2014: https://scardio.ru/content/Guidelines/recomend_2_rkj_15.pdf


Review

For citations:


Palshina A.M., Gryaznukhina N.N., Barashkov P.E., Ananieva V.A., Silina N.N., Sosin L.K., Pavlov D.A. REPERFUSION SYNDROME IN ENDOVASCULAR MYOCARDIAL REVASCULARIZATION: A CLINICAL OBSERVATION. Vestnik of North-Eastern Federal University. Medical Sciences. 2023;(1):66-72. (In Russ.) https://doi.org/10.25587/SVFU.2023.30.1.004

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ISSN 2587-5590 (Online)