A CLINICAL CASE OF THE COMBINED COURSE OF THE NEW CORONAVIRAL INFECTION COVID-19 AND VIRAL HEPATITIS A

Abstract

At the end of December 2019, an outbreak of unknown pneumonia caused by the new coronavirus SARS-CoV-2 began in the People’s Republic of China. On February 11, 2020, the World Health Organization assigned the official name of SARS-CoV-2 infection - COVID-19 (“CoronaVirus Disease 2019” - a disease caused by the new coronavirus 2019). Pneumonia is the leading clinical form of COVID-19. However, as the COVID-19 pandemic spread and the analysis of clinical data, the patients began to emit symptoms that are not characteristic of “abnormal” pneumonia. Neurological manifestations, skin changes, eye lesions, etc. have been described. The generalized accumulated data and clinical experience indicate that elderly patients and persons with chronic diseases such as diabetes mellitus, cardiovascular diseases and liver diseases, obesity may be susceptible to higher risks of developing more severe forms of the disease COVID-19 [1]. Among the possible factors of liver damage, a virus-induced effect, systemic inflammation (“cytokine storm”), hypoxia, hypovolemia, hypotension in shock, drug hepatotoxicity, etc. are considered. Acute hepatitis develops very rarely.