The contribution of the gender factor to the course of infiltrative tuberculosis: the case of the Sakha Republic (Yakutia)

Abstract

The article describes the contribution of the gender factor to the course of infiltrative tuberculosis, based on the analysis of medical records of 58 patients who were admitted to the Respiratory Tuberculosis Department of the Phthisiology Research-practical Center in 2018. All the patients demonstrated symptoms of intoxication of varying intensity. So, upon admission, men complained of weakness in 24 % of cases, women complained of weakness in 21 %. It should be noted that sweating occurred in 14 % of women and 3 % of men, weight loss was observed in 14 % of male patients, women lost weight in 7 % of cases. When considering the prevalence of the tuberculous process, it was revealed that the process was widespread in most patients, since it was localized in 1 segment - 48 % in men and 38 % in women, in 2 segments - 45 % and 52 %, respectively. It should also be noted that the defeat of the whole lobe of the lung was observed in 5 men and 7 women. In the study of drug resistance, mono-resistance was observed in 14 % of men, and in 7 % of women, multidrug resistance was registered in 24 % of cases in men and in 14 % in women. When considering concomitant diseases, it was revealed that 17 % of men suffer from alcohol dependence, 17 % of women suffer from chronic hepatitis, it should be noted that chronic cholecystitis in women was 3 times more common than in men; however, despite this, it is noted that clinical x-ray improvement occurred faster in women than in men. When studying the effectiveness of treatment, it was found that the closure of the decay cavities in men was achieved after 4 months in 28 % of the cases, in women - in 24 %. The cessation of bacterial excretion in female patients occurred after 3-4 months in 42 %, in men - in 35 % of the cases.