HELLP SYNDROME (CLINICAL CASE)

The article describes a clinical case in which the patient was diagnosed with HELLP syndrome. The article provides a brief description of the etiology, pathogenesis and classification of HELLP syndrome. In addition, the article describes the onset of this disease in detail - specific clinical and laboratory changes, as well as information about clinical and laboratory changes throughout the treatment of the disease. Diagnostic features were observed: clinical symptoms (epigastric or right upper quadrant of the abdomen pain, nausea and/or vomiting, headache, sensitivity during palpation in the right upper quadrant of the abdomen, diastolic blood pressure above 110 mmHg, edema, arterial hypertension), laboratory diagnostic features (massive proteinuria of more than 2 g/l, massive intravascular hemolysis, microscopic presence of fragmented red blood cells (schizocytes), LDH level of more than 600 IU/ l, level of indirect bilirubin more than 1 2 μmol/ l, a decreased level of haptoglobin, a decreased level of platelets less than 100 * 109/ l, ALT, AST more than 70 ME/ l) and ways of intensive care, in particular, treatment of massive intravascular hemolysis. The importance of the correct diagnosis made on time and early start of pathogenetic therapy was noted.

HELLP синдром, HELLP syndrome, massive intravascular hemolysis, thrombotic microangiopathy, obstetrics, delivery, plasma exchange, preeclampsia, hemolytic anemia, thrombocytopenia, arterial hypertension

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