AGE-RELATED CHANGES IN BRAIN STEM VOLUME IN YOUNG-OLD AGE AND OLD-OLD AGE

One of the tasks of a developed society with a high standard of living is to increase life expectancy. It is worth understanding that the increasing number of young-old and old-old population causes the importance of developing gerontology and geriatrics. Causes and consequences of aging of the central nervous system departments have been studied sufficiently; nevertheless, anatomical data on the brain structures in the age aspect, namely on changes in the brain stem volume, are poorly presented. The aim of the investigation was to carry out a comparative analysis of brain stem volume parameters in young-old and old-old men and women according to magnetic resonance imaging data. The data of magnetic resonance imaging were analyzed in 94 patients examined in the Department of Radiation Diagnostics of State Autonomous Healthcare Institution of Perm Krai «City Clinical Hospital №» in the period of 2020-2022. The patients were divided into two groups according to age periodization. The first group consists of young-old people: 27 men aged 61-74 years and 23 women aged 56-73 years. The second group was represented by old-old individuals: 23 men aged 75-88 and 21 women aged 75-88. The study sample included persons without pathologies of central and peripheral nervous system, with absence of alcohol or drug addiction, with skulls of medium shape – mesocranes. The volume of the brain stem was determined in the 3D reconstruction mode. A tendency to the prevalence of parameters of the trunk volume in the young-old men and women in comparison with representatives of the old-old age (p>0.05) was established. In each age group studied, there was a tendency for prevalence of brain stem volume parameters in men compared to women (p>0.05). Thus, the obtained data add to the scientific knowledge about age-related anatomical features of the brain stem, which, in turn, will allow their use in assessing its volume in elderly and senile patients.

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