REPERFUSION SYNDROME IN ENDOVASCULAR MYOCARDIAL REVASCULARIZATION: A CLINICAL OBSERVATION
https://doi.org/10.25587/SVFU.2023.30.1.004
Abstract
CHD retains a leading position worldwide due to high rates of mortality and disability. The best and proven strategy aimed at saving the damaged myocardium in ST-segment elevation myocardial infarction (STEMI) is rapid and effective reperfusion of the ischemic heart muscle through primary percutaneous coronary intervention (PCI) or pharmacoinvasive therapy. However, the restoration of blood flow by itself can lead to reperfusion damage to the affected myocardium. In acute coronary catastrophe caused by acute occlusion of the coronary artery, myocardial stun and hibernation develop locally. With STEMI, hibernation can be observed both near the infarction zone and in more distant areas of the myocardium. In patients with STEMI, the appearance of life-threatening arrhythmias (ventricular tachycardia and ventricular fibrillation) occurs in 4.3 % of cases and is primarily associated with reperfusion after PCI. In most cases, arrhythmias that occur during the procedure are stopped spontaneously; however, when accompanied by ventricular tachyarrhythmia, hemodynamic instability, the use of electric pulse therapy (EIT) is provided. The article presents a clinical case of a patient C., 52, whose reperfusion syndrome manifested itself by the development of life-threatening ventricular tachyarrhythmias: unstable ventricular tachycardia «torsade de points» with transformation into VF, which were stopped by EIT: defibrillation. No recurrence of ventricular tachyarrhythmia was observed in this patient. At this stage, we explain the resulting episode of unstable ventricular tachycardia with short-term myocardial stunning due to short-term ischemia and myocardial damage.
About the Authors
A. M. PalshinaRussian Federation
PALSHINA Aida Mikhailovna – Candidate of Medical Sciences, Associate Professor, Department of Hospital
Therapy, Occupational Diseases and Clinical Pharmacology, Institute of Medicine
677000, Yakutsk, ul. Oyunskogo, 27
phone: 8(914)226-59-39
N. N. Gryaznukhina
Russian Federation
GRYAZNUKHINA Natalia Nikolaevna – Candidate of Medical Sciences, Associate Professor, Department
of Hospital Therapy, Occupational Pathology, Clinical Pharmacology, Institute of Medicine
677000, Yakutsk, ul. Oyunskogo, 27
phone: 8(929)648-81-67
P. E. Barashkov
Russian Federation
BARASHKOV Petr Egorovich – student, Institute of Medicine
677008, Yakutsk, Sergelyakhskoe shosse 4 km, 13
phone: 8(964)4227056
V. A. Ananieva
Russian Federation
ANANYEVA Victoria Anatolyevna – student, Institute of Medicine
677010, Yakutsk, ul. Ya. Potapova, 19/1, apt. 31
phone: 8(964)4227056
N. N. Silina
Russian Federation
SILINA Natalya Nikolaevna – Head, Department of Cardiology with Intensive Care for Patients with Acute
Coronary Syndrome
677027, Yakutsk, ul. Ordzhonikidze, 46/1, apt. 29
phone: 8(964)4235888
L. K. Sosin
Russian Federation
SOSIN Leonid Konstantinovich – X-ray surgeon, Department of Radiation Diagnostics
677010, Yakutsk, Sergelyakhskoe shosse, 4
Phone: 8(914)8227938
D. A. Pavlov
Russian Federation
PAVLOV Dmitry Anatolyevich – anesthesiologist-resuscitator, Intensive care Unit
677001, Yakutsk, ul. P. Osipenko, 5B, building 1, apt. 169
Phone: 8(962)7367020
References
1. Khan M.A., Hashim M.J., Mustafa Y. et al Global Epidemiology of Ischemic Heart. Disease: Results from the Global Burden of Disease Study. Cureus. 2020;12(7) ce9349 doi: 10.7759/cureus.9349
2. Federal project «Fight against cardiovascular diseases»: https://www.roszdravnadzor.gov.ru/i/upload/images/2018/7/25/1532512237.26174-1-15781.pdf
3. Regional program “Fight against cardiovascular diseases in the Republic of Sakha (Yakutia) for 2019-2024”: https://minzdrav.sakha.gov.ru/uploads/ckfinder/userfiles/files/
4. Clinical recommendations “Acute myocardial infarction with ST segment elevation electrocardiogram”, 2020: https://cardioweb.ru/files/glavny-kardiolog/rekomendation
5. I.E. Vereshchagin, R.S. Tarasov, E.I. Vereshchagin, V.I. Ganyukov “Methods of cardioprotection in myocardial infarction. The current state of the issue”: https://cyberleninka.ru/article/n/metody-kardioprotektsiipri-infarkte-miokarda-sovremennoe-sostoyanie-voprosa
6. Hochachka R.W. Metabolic arrest. Intensive. Care. Med.1986; 12(3): 127-133: https://sciencejournals.ru/view-article/?j=evolbkf&y=2019&v=55&n=5&a=EvolBKF1905002Burykh
7. ESC/EACTS Recommendations on Myocardial revascularization, 2014: https://scardio.ru/content/Guidelines/recomend_2_rkj_15.pdf
Review
For citations:
Palshina A.M., Gryaznukhina N.N., Barashkov P.E., Ananieva V.A., Silina N.N., Sosin L.K., Pavlov D.A. REPERFUSION SYNDROME IN ENDOVASCULAR MYOCARDIAL REVASCULARIZATION: A CLINICAL OBSERVATION. Vestnik of North-Eastern Federal University. Medical Sciences. 2023;(1):66-72. (In Russ.) https://doi.org/10.25587/SVFU.2023.30.1.004