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THE APPLICATION OF THE SCREENING MPEST GUESTIONNAIRE IN EARLY DIAGNOSTICS OF PSORIATIC ARTHRITIS IN PATIENTS WITH PSORIASIS IN THE DERMATOLOGICAL CLINICAL PRACTICE

https://doi.org/10.25587/SVFU.2021.24.3.006

Abstract

Psoriasis is a chronic immune-associated disease of a multifactorial nature with a dominant role in the development of genetic factors, characterized by accelerated proliferation of keratinocytes and a violation of their differentiation, an imbalance between pro-inflammatory and anti-inflammatory cytokines, with frequent pathological changes in the musculoskeletal system. In the territory of the Sakha Republic (Yakutia) in 2020, the incidence rate of psoriasis was 4.3 per 1,000 population, including 0.3 with psoriatic arthritis. The aim of the study was to evaluate the effectiveness of the mPEST questionnaire for the early diagnosis of psoriatic arthritis in patients with psoriasis who are registered at a dispensary in a polyclinic. Materials and methods. The study included 73 patients (44 men and 29 women) with psoriasis who are registered at the State Medical Institution of the SR (Ya) “Yakut Skin and Venereological Dispensary”. The average age of the examined patients was 42.4±11.47 years. The duration of psoriasis ranged from 4 years to 63 years (18.2±14.1 years). All patients underwent a standard dermatological examination. All patients included in the study completed a modified mPEST screening questionnaire to detect psoriatic arthritis. Depending on the results of the questionnaire, patients were referred for examination to a rheumatologist. Results and discussion. As a result of using the mPEST questionnaire, psoriatic arthritis was suspected in 27 (36.9 %) patients out of 73 respondents. At the same time, only 26 (96.2 %) patients met the CASPAR classification criteria. The frequency of diagnosed psoriatic arthritis was 36.2 %. Conclusions. The use of the mPEST questionnaire in patients with psoriasis can significantly improve the early diagnosis of psoriatic arthritis.

About the Authors

V. I. Fedorova
Institute of Medicine, M. K. Ammosov North-Eastern Federal University
Russian Federation


N. A. Savvina
Institute of Medicine, M. K. Ammosov North-Eastern Federal University
Russian Federation


N. I. Suchanova
Yakut Skin and Venereological Dispensary
Russian Federation


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For citations:


Fedorova V.I., Savvina N.A., Suchanova N.I. THE APPLICATION OF THE SCREENING MPEST GUESTIONNAIRE IN EARLY DIAGNOSTICS OF PSORIATIC ARTHRITIS IN PATIENTS WITH PSORIASIS IN THE DERMATOLOGICAL CLINICAL PRACTICE. Vestnik of North-Eastern Federal University. Medical Sciences. 2021;(3):39-48. (In Russ.) https://doi.org/10.25587/SVFU.2021.24.3.006

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