VILYUI ENCEPHALOMYELITIS: ORGANIZATION OF CLINICAL AND EPIDEMIOLOGICAL RESEARCH IN YAKUTIA
https://doi.org/10.25587/SVFU.2021.24.3.003
Abstract
Diagnosing Vilyui encephalomyelitis is complicated by its clinical polymorphism, lack of reliable and specific laboratory diagnostic tests, as well as the presence in Yakutia of other neurodegenerative diseases with clinical manifestations that partially overlap the manifestations of Vilyui encephalomyelitis. The article presents the history of the discovery and organizational forms of work with a previously unknown disease: Vilyui encephalomyelitis. The study determined the roles of the disease discoverer Prokopy Andreevich Petrov, of prominent Russian and foreign scientists: Elena Semyonovna Sarmanova, Mikhail Petrovich Chumakov, Afanasy Vladimirovich Vladimirtsev, and a Nobel Prize winner Carlton Gajdusek. The persistent efforts of doctors to isolate patients with acute and slowly progressive forms of Vilyui encephalomyelitis in specialized medical institutions helped to contain the further spread of this deadly disease to other parts of the Russian Federation and around the world.
About the Author
L. G. Goldfarb
Department of Pathology and Molecular Medicine, Queen’s University, Kingston General Hospital, Kingston
Russian Federation
Russian Federation
References
1. Ходос К.-Б. Г. Учебник нервных болезней. Издательство Медицинской Литературы. Москва, 1948. [Khodos K-B.G. Textbook on Neurological Disorders. Medical Literature. Moscow, 1948. (In Russian)].
2. Шаповал А.Н. Вилюйский энцефаломиелит. Якутск, Якутское Книжное Издательство. 1959, 156 стр. [Shapoval AN. Viliuisk encephalomyelitis. Yakutsk: Yakutsk Publishing House. 1959, 156 pages. (In Russian)].
3. Сарманова Е.С., Чумаченко Г.Г. К этиологии Вилюйского энцефаломиелита. Вопр. Психиатр. и Невропатол. (Ленинград). 1959; 5:15-20. [Sarmanova E.S., Chumachenko G.G. A study of the etiology of Viliuisk encephalomyelitis. Vopr Psych. Nevropat. (Leningrad). 1959; 5:15-20. (In Russian)].
4. Casals J. Immunological characterization of Vilyuisk human encephalomyelitis virus. Nature 1963; 200:339-341.
5. Lipton H.L. Human Vilyuisk encephalitis. Rev Med Virol. 2008;18(5):347-52.
6. Чумаков М.П., Петров П.А., Владимирцев А.И., Сарманова Е.С., Гольдфарб Л.Г., Тазлова Р.С. и др. Итоги переписи больных Вилюйским энцефаломиелитом (1971-1972 гг.) и перспективы исследования природы этого заболевания. В: М.П. Чумаков (ред.). Актуальные Проблемы Вирусологии и Профилактики Вирусных Заболеваний. Москва, Академия Медицинских Наук СССР, 1972, 191-193. [Chumakov M.P., Petrov P.A., Vladimirtsev A.I., Sarmanova E.U., Goldfarb L., Tazlova R.S., et al. The results of the census of patients with Viliuisk encephalomyelitis (1971-1972) and the prospects for studies on the nature of the disease. In: M.P. Chumakov (ed.). Current Problems in the Virology and Prevention of Viral Diseases. Moscow, The USSR Academy of Medical Sciences. 1972, 191-193. (In Russian)].
7. Петров П.А. Клиническая картина острой стадии Вилюйского энцефалита (энцефаломиелита). Якутск, Якутское Книжное Издательство. 1964, 122 cтр. [Petrov PA. Clinical features of the acute phase of Viliuisk encephalitis (encephalomyelitis). Yakutsk: Yakutsk Publishing House. 1964, 122 pages. (In Russian)].
8. Колпакова Т.А. Эпидемиологическое обследование Вилюйского округа ЯАССР. Материалы Комиссии по изучению Якутской Автономной Советской Социалистической Республики. Ленинград, Государственное Издание. 1933, 112 стр. [Kolpakova T.A. Epidemiological survey of the Viliuisk Region, Yakut Autonomous Soviet Socialist Republic. Transactions of a Governmental Commission for Investigations of the Yakut Autonomous Soviet Socialist Republic. Leningrad, Government Printing House. 1933; 112 pages. (In Russian)].
9. Зубри Г.Л., Уманский К.Г., Савинов А.П., Коротов М.Н., Баранов В.А. О нозологической принадлежности бохорора. Генетика (Москва). 1977; 13(10):1843-54. [Zubri G.L., Umanskiy K.G., Savinov A.P., Korotov M.N., Baranov V.A. Nozological classification of bokhoror. Genetika (Moscow). 1977; 13:1843-1854. (In Russian)].
10. Гольдфарб Л.Г., Федорова Н.И., Чумаков М.П., Петров П.А., Владимирцев А.И., Иванова А.И. Соотношение наследственности и средовых факторов в этиологии Вилюйского энцефаломиелита: Сообщение I. Частота больных в семьях. Генетика (Москва). 1979; 8:1502-12. [Goldfarb L.G., Fedorova N.I., Chumakov M.P., Petrov P.A., Vladimirtsev A.I., Ivanova A.I. Heredity and environment in the etiology of Viliuisk encephalomyelitis. 1. Affected families. Genetika (Moscow). 1979; 15:1502-12. (In Russian)].
11. Marsden K. On sledge and horseback to outcast Siberian lepers. New York, Cassel Publishing Company. 1891, 291 pages.
12. Петров П.А. Вилюйский энцефалит. Новосибирск, Наука. 1987, 132 стр. [Petrov P.A. Viliuisk encephalitis. Novosibirsk, Nauka. 1987, 132 pages. (In Russian)].
Review
For citations:
Goldfarb L.G. VILYUI ENCEPHALOMYELITIS: ORGANIZATION OF CLINICAL AND EPIDEMIOLOGICAL RESEARCH IN YAKUTIA. Vestnik of North-Eastern Federal University. Medical Sciences. 2021;(3):19-25. (In Russ.) https://doi.org/10.25587/SVFU.2021.24.3.003
Views:
128
Email this article 