COGNITIVE IMPAIRMENT IN HEREDITARY ATAXIAS: LITERATURE REVIEW
https://doi.org/10.25587/2587-5590-2024-1-49-55
Abstract
Hereditary ataxias are a clinically and genetically heterogeneous group of nervous system diseases, mostly progressive and mainly clinically characterized by coordination disorders due to degeneration of the corresponding afferent and efferent neuronal systems. Hereditary ataxias are divided into autosomal dominant, autosomal recessive, and X-linked recessive forms; sporadic forms with unspecified or unknown transmission mechanism are also distinguished. In this article, we review the impact of hereditary ataxias on the cognitive function. We present data from various studies that collectively shed light on the complex relationships between motor and cognitive impairments in patients with hereditary ataxias.
About the Authors
A. M. Khafizova
Yakutsk Scientific Center for Complex Medical Problems
Russian Federation
Russian Federation
KHAFIZOVA Anastasiya Marselievna – Junior Researcher, Laboratory of Neurodegenerative Diseases, Department of Epidemiology of Chronic Non-Communicable Diseases,
Yakutsk.
T. K. Davydova
Clinic of the Yakutsk Scientific Center for Complex Medical Problems
Russian Federation
Russian Federation
DAVYDOVA Tatyana Kimovna – Cand. Sci. (Medicine), Leading Researcher, Head of Laboratory of Neurodegenerative Diseases, Head of the Center of Neurodegenerative Diseases,
Yakutsk.
M. A. Varlamova
Yakutsk Scientific Center for Complex Medical Problems
Russian Federation
Russian Federation
VARLAMOVA Marina Alekseevna – Researcher, Laboratory of Neurodegenerative Diseases, Department of Epidemiology of Chronic Non-Communicable Diseases,
Yakutsk.
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For citations:
Khafizova A.M., Davydova T.K., Varlamova M.A. COGNITIVE IMPAIRMENT IN HEREDITARY ATAXIAS: LITERATURE REVIEW. Vestnik of North-Eastern Federal University. Medical Sciences. 2024;(1):49-55. (In Russ.) https://doi.org/10.25587/2587-5590-2024-1-49-55
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