THE LEVEL OF TOTAL IMMUNOGLOBULIN E IN PATIENTS WITH ALLERGIC DISEASES

Abstract

The priority task for the modern medicine is timely diagnosis, treatment and prevention of diseases. This article examines the level of total immunoglobulin E in patients with allergic diseases such as bronchial asthma, allergic rhinitis, atopic dermatitis, etc.

The authors set a goal to investigate changes in the level of total immunoglobulin E in patients with allergic diseases. We analyzed the primary results of determining total IgE by enzyme immunoassay.

When analyzing the primary result of total IgE in a population with a history of allergic disease (atopic dermatitis, allergic rhinitis, allergic bronchial asthma, etc.), normal levels were observed in 41 % of patients; an increased level was observed in 144 patients up to 500 IU / ml in 46 % and over 500 IU / ml – 13 %.

Important in the diagnosis of type 1 allergic reactions is the level of total IgE, exceeding the maximum values (above 500 IU / ml). In other types of allergic reactions, the level of total IgE may be increased, but does not exceed the level of more than 500 IU / ml, even in the acute course of the disease.

Interpretation of changes in the total level of immunoglobulin E, along with other data from the study of the immune status, can significantly help in screening for allergic diseases. When diagnosing an increased general level of immunoglobulin E and with early involvement of preventive and therapeutic measures, it is possible to significantly improve the condition of a patient with atopic forms of allergy and avoid serious complications.