CLINICAL-MICROBIOLOGICAL CHARACTERISTICS OF LOCAL FORMS OF NEONATAL PURULENT-INFLAMMATORY DISEASES

Abstract

For a long time, many researchers have noted a high incidence of purulent inflammatory diseases (PID) in newborns, which occupy one of the leading positions in the structure of infectious diseases of the neonatal period. The causes are anatomical and physiological features of the skin structure; subcutaneous fat of newborns; a developed network of blood and lymphatic capillaries; features of the skin microbiome; the presence of umbilical wound; reduced resistance to infections; infectious diseases of the mother, in particular, urogenital infections during pregnancy and childbirth; as well as the widespread occurrence of gram-negative enterobacteria in medical establishments (such as E. Coli, Klebsiella spp., Proteus). In addition, in the etiological structure of purulent-inflammatory diseases in newborn children, there is a high proportion of chlamydia and mycoplasmosis, which contribute to a more severe flow of diseases. Purulent-inflammatory diseases of newborns are divided into two groups: local and generalized forms. In the structure of purulent-inflammatory diseases in full-term newborns, 18-25 % are local forms of purulent infection of the skin, subcutaneous fiber and umbilical wound, which is the source of the generation of the purulent process, the lethality of which, according to various authors, is from 30 to 40 %. This article provides data on the peculiarities of clinical manifestations of local forms of newborn with PID and their etiological structure.