PATHOGENETIC APPROACH TO THE USE OF ANTIOXIDANT DRUGS IN THE TREATMENT OF DIABETES MELLITUS
https://doi.org/10.25587/SVFU.2023.31.2.009
Abstract
Diabetes mellitus (DM) is a complex, multifactorial metabolic disease that tends to steadily increase and affects the quality and life expectancy of the population. Cardiovascular complications accompanying this endocrine pathology most often lead to early disability and are the cause of death of patients. The main role in the pathogenesis of diabetic angiopathies belongs to the manifestation of free radical oxidation (SRO). Based on this premise, the purpose of our study was to study the effectiveness of taking an antioxidant (AO) of plant origin – dihydroquercetin (DHA) in the conditions of complex therapy of patients with type 2 diabetes living in the northern region. 132 people were examined, of which 78 patients with type 2 diabetes were included in the main group, 54 representatives of the alien population of the Khanty-Mansi Autonomous Okrug – Yugra were included in the control group (conditionally healthy, without metabolic disorders). The content of lipid peroxidation products in the blood of all the examined persons was determined
About the Authors
V. I. Korchin
Khanty-Mansiysk State Medical Academy
Russian Federation
Russian Federation
KORCHIN Vladimir Ivanovich – Doctor of Medical Sciences, Professor, Honored Worker of the Higher School of the Russian Federation, Professor, Department of Physiology and Sports Medicine
628001, Khanty-Mansiysk, ul. Yamskaya, 12, kv. 45
Tel.: +7 (922) 253-49-16
T. Ya. Korchina
Khanty-Mansiysk State Medical Academy
Russian Federation
Russian Federation
KORCHINA Tatiana Yakovlevna – Doctor of Medical Sciences, Professor, Department of General and Faculty Surgery
628001, Khanty-Mansiysk, ul. Yamskaya, 12, kv. 45
Tel.: +7 (922) 433-29-52
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Review
For citations:
Korchin V.I., Korchina T.Ya. PATHOGENETIC APPROACH TO THE USE OF ANTIOXIDANT DRUGS IN THE TREATMENT OF DIABETES MELLITUS. Vestnik of North-Eastern Federal University. Medical Sciences. 2023;(2):75-84. (In Russ.) https://doi.org/10.25587/SVFU.2023.31.2.009
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