A case of imported visceral leishmaniasis in clinical practice
https://doi.org/10.25587/2587-5590-2025-3-56-62
Abstract
Leishmaniasis is a parasitic natural focal zoonotic transmissible disease common in tropical and subtropical countries; it is caused by parasitic protozoa of the genus Leishmania, which are transmitted to humans through mosquito bites. The most severe form of the disease is visceral leishmaniasis, which affects the organs of the reticuloendothelial system. The lack of alertness in terms of clinical and laboratory diagnostics of this disease in non-endemic areas sometimes leads to errors in diagnostic verification. A rare imported clinical case of visceral leishmaniasis associated with fever, hepatosplenomegaly, generalized lymphadenopathy, and hematological syndrome in the form of three-line cytopenia is presented. Only detection of the pathogen in bone marrow puncture allowed us to make the correct diagnosis. Low awareness of doctors and the lack of systematic riskoriented monitoring of exotic diseases often complicates the timely diagnosis of leishmaniasis, which leads to an unfavorable clinical course of the disease and, in some cases, a fatal outcome.
About the Authors
E. P. TikhonovaRussian Federation
Tikhonova Elena Petrovna, Dr. Sci. (Medicine), Professor, Head of the Department of Infectious Diseases and Epidemiology with a Course of Postgraduate Education
Krasnoyarsk, phone: +7-908-014-33-43
E. N. Anisimova
Russian Federation
Anisimova Elena Nikolaevna, Cand. Sci. (Medicine), Associate Professor, Leading Researcher, Research Institute for Medical Problems of the North
Krasnoyarsk, Tel. mob. +7-913-173-87-89
N. S. Minoranskaya
Russian Federation
Minoranskaya Natalia Sergeevna, Dr. Sci. (Medicine), Docent, Professor, Department of Infectious Diseases and Epidemiology with a Course of Postgraduate Education
Krasnoyarsk, phone: +7(391) 27-127-66
References
1. Novosad E.V., Belimenko V.V., Shamsheva O.V., et al. Clinical case of imported visceral leishmaniasis in a child in Moscow. Pediatrics. 2018; 98(1):250–253 (in Russian). DOI:10.24110/0031-403X-2019-98-1-250-253.
2. Obgolts Yu.N., Samoilova N.G., Fed S.S., et al. Infectious pathology in the practice of a hematologist: visceral leishmaniasis in an HIV-infected patient. Siberian Scientific Medical Journal. 2019;39(1):72–75 (in Russian). DOI:10.15372/SSMJ20190110.
3. Al Mahfoud R., Siprov A.V., Romanova E.V., et al. Clinical and pharmacological aspects of leishmaniasis. Modern problems of science and education. 2023;(3):103 (in Russian). DOI:https://doi.org/10.17513/spno.32596.
4. Brovko M.Yu., Akulkina L.A., Potapov P.P., et al. Visceral leishmaniasis: difficult differential diagnosis in therapeutic practice. Therapeutic archive. 2020;92(11):117–121 (in Russian). DOI:10.26442/00403660.2020.11.000619.
5. Chuelov A.U., Rossina A.L., Lebedev T.M., et al. Parasitic diseases in the practice of a pediatric multidisciplinary hospital. Childhood infections. 2020;19(1);48–53 (in Russian). https://doi.org/10.22627/2072-8107-2020-19-1-48-53.
6. Potapenko V.G., Antonov M.M., Vinogradova N.V., et al. Secondary hemophagocytic syndrome as a complication of visceral leishmaniasis: a clinical observation. Oncohematology. 2022;17(3):89–97 (in Russian). DOI:10.17650/1818-8346-2022-17-3-89-97.
7. Bekhtereva M.K., Kozlov S.S., Komarova A.M., et al. Visceral leishmaniasis in a child: difficulties in diagnosis and treatment. Journal of Infectology. 2019;11(3):118–125 (in Russian). DOI:10.22625/2072-6732-2019-11-3-118-125.
Review
For citations:
Tikhonova E.P., Anisimova E.N., Minoranskaya N.S. A case of imported visceral leishmaniasis in clinical practice. Vestnik of North-Eastern Federal University. Medical Sciences. 2025;(3):56-64. (In Russ.) https://doi.org/10.25587/2587-5590-2025-3-56-62