ANTIMICROBIAL ACTIVITY OF GRAPHENE OXIDE
https://doi.org/10.25587/SVFU.2019.3(16).39459
Abstract
Materials with antimicrobial properties are interesting for medical production. However, the safety of modern materials based on ammonium compounds, silver ions and titanium oxide does not meet of standards. Graphene oxide is a promising candidate for biomedical research because it exhibits good antimicrobial properties with minimal cytotoxicity against human cells. This paper presents the results of our own research on the antimicrobial properties of graphene oxide. It is shown that the suspension of graphene oxide has a bactericidal and fungicidal effect, due to damage the membrane of microbial cells.
About the Authors
M. N. Egorova
Institute of Physics and Technologies, M.K.Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
L. A. Tarasova
Institute of Medicine M.K.Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Y. A. Ahremenko
Institute of Medicine M.K.Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
V. I. Ilarova
Institute of Medicine M.K.Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
F. D. Vasileva
Institute of Physics and Technologies M.K.Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
S. A. Smagulova
Institute of Physics and Technologies M.K.Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
References
1. Hu, W. Graphene-based antibacterial paper / W. Hu, C. Peng, W. Luo, X. Li, D. Li, Q. Huang, C. Fan // ACS nano. - 2010. - № 4 (7). - P. 4317-4323.
2. Tang, L. Bottom-up synthesis of large-scale graphene oxide nanosheets / L. Tang, X. Li, R. Ji, K. Teng, G. Tai, J. Ye, C. Weia, S. Lau // Journal of Materials Chemistry. - 2012. - № 22. - P. 5676-5683.
3. Lee, C. Measurement of the Elastic Properties and Intrinsic Strength of Monolayer Graphene, C. Lee, X. Wei, J. W. Kysar, J. Hone // Science. - 2008. - № 321 (5887). - P. 385-388.
4. Stankovich, S. Graphene-based composite materials / S. Stankovich, D. A. Dikin, G. H. B. Dommett, K. M. Kohlhaas, E. J. Zimney, E. A. Stach, R. D. Piner, S. T. Nguyen, R. S. Ruoff // Nature. - 2006. - № 442 (7100). P. 282-286.
5. Balandin, A. A. Superior Thermal Conductivity of Single-Layer Graphene / A. A. Balandin, S. Ghosh, W. Bao, I. Calizo, D. Teweldebrhan, F. Miao, C. N. Lau // Nano letters. - 2008. - № 8 (3). P. 902-907.
6. Novoselov, K.S. Electric field effect in atomically thin carbon films / K.S. Novoselov, A K. Geim, S.V. Morozov, D. Jiang, Y. Zhang, S.V. Dubonos, I.V. Grigorieva, A.A. Firsov // Science. - 2004. - № 306 (5696). P. 666-669.
7. Novoselov, K.S. Two-dimensional gas of massless Dirac fermions in grapheme / K.S. Novoselov, A.K. Geim, S.V. Morozov, D. Jiang, M.I. Katsnelson, I.V. Grigorieva, S.V. Dubonos, A.A. Firsov // Nature. - 2005. - № 438. - P. 197-200.
8. Zhang, Y. Experimental Observation of Quantum Hall Effect and Berry’s Phase in Graphene / Y. Zhang, Y.-W. Tan, H.L. Stormer, P. Kim // Nature. - 2005. - № 438. P. 201-204.
9. Geim, A. K. Graphene: Status and Prospects/ Geim A. K. // Science. - 2009. - № 324. P. 1530-1534.
10. Zhang, Y. Electric Field Modulation of Galvanomagnetic Properties of Mesoscopic Graphite / Y. Zhang, J.P. Small, M.E.S. Amori, P. Kim // Physical Review Letters. - 2005. - № 94. - P. 176803-1-176803-4.
11. Li, D. Processable aqueous dispersions of graphene nanosheets/ D. Li, M.B. Muller, S. Gilje, R.B. Kaner, G.G. Wallace // Nature Nanotechnology. - 2008. - № 3. P. 101-105.
12. Lin, Y.M. 100-GHz Transistors from Wafer-Scale Epitaxial Graphene / Lin Y.M., C. Dimitrakopoulos, K.A. Jenkins, D.B. Farmer, H.Y. Chiu, A. Grill, P. Avouris // Science. - 2010. - № 327. - P. 662
13. Dong, X. Electrical Detection of DNA Hybridization with Single-Base Specificity Using Transistors Based on CVD-Grown Graphene Sheets / X. Dong, Y. Shi, W. Huang, P. Chen, L.-J. Li // Advanced Materials. - 2010. - № 22. - P. 1649-1653.
14. He, Q. Centimeter-Long and Large-Scale Micropatterns of Reduced Graphene Oxide Films: Fabrication and Sensing Applications, Q. He, H.G. Sudibya, Z. Yin, S. Wu, H. Li, F. Boey, W. Huang, P. Chen, H. Zhang // American Chemical Society Nano. - 2010. - № 4. - P. 3201-3208.
15. Wang, X. Transparent Carbon Films as Electrodes in Organic Solar Cells / X. Wang, L. Zhi, N. Tsao, Z. Tomovic, J. Li, K. Mullen// Angewandte Chemie Internatiomal Edition. - 2008. - № 47. - P. 2990-2992.
16. Wang, X. Transparent, Conductive Graphene Electrodes for Dye-Sensitized Solar Cells / X. Wang, L. Zhi, K. Mullen// Nano Letters. - 2008. - № 8. - P. 323-327.
17. Yin, Z. Electrochemical Deposition of ZnO Nanorods on Transparent Reduced Graphene Oxide Electrodes for Hybrid Solar Cells / Z. Yin, S. Wu, X. Zhou, X. Huang, Q. Zhang, F. Boey, H. Zhang // Small. - 2010. - № 6. - P. 307-312.
18. Schedin, F. Detection of individual gas molecules adsorbed on grapheme / F. Schedin, A.K. Geim, S.V. Morozov, E.W. Hill, P. Blake, M.I. Katsnelson, K.S. Novoselov // Natural Materials. - 2007. - № 6. - P. 652-655.
19. Wang, Z. Direct Electrochemical Reduction of Single-Layer Graphene Oxide and Subsequent Functionalization with Glucose Oxidase / Z. Wang, X. Zhou, J. Zhang, F. Boey, H. Zhang// The Journal of Physical Chemistry C. - 2009. - № 113. - P. 14071-14075.
20. Geim, A.K. The Rise of Graphene / A.K. Geim, K.S. Novoselov // Nature of Materials. - 2007. - № 6. - P. 183-191.
21. Yang, K. Graphene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy / K. Yang, S. Zhang, G. Zhang, X. Sun, S.-T. Lee, Z. Liu // Nano Letters. - 2010. - № 10. - P. 3318-3323.
22. Akhavan, O. Toxicity of Graphene and Graphene Oxide Nanowalls against Bacteria / O. Akhavan, E. Ghaderi // American Chemical Society Nano. - 2010. - № 4. - P. 5731-5736.
23. Zhang, Y.B. Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived PC12 cells/ Y.B. Zhang, S.F. Ali, E. Dervishi, Y. Xu, Z.R. Li, D. Casciano, A.S. Biris// American Chemical Society Nano. - 2010. - № 4. -P. 3181-3186.
24. Hummers, W. S. Preparation of Graphitic Oxide / W. S. Hummers, R. E. Offeman // Journal of the American Chemical Society. - 1958. - № 80. - P. 1339-1339.
25. Alexandrov, G. N. Thin partially reduced oxide-graphene films: Structural, optical, and electrical properties / G. N. Alexandrov, S.A. Smagulova, A.N. Kapitonov, F.D. Vasilieva, I.I Kurkina, P.V. Vinokurov, V.D. Timofeev, I.V. Antonova // Nanotechnologies in Russia. - 2014. - № 9 (5-6). - P. 18-22.
26. Kapitonov, A.N. Characterization of Graphene Oxide Suspension for Fluorescence Quenching in DNA-Diagnostics / A.N. Kapitonov, G.N. Alexandrov, F.D. Vasileva, S.A. Smagulova, V.B. Timofeev, N.R. Maksimova, A.A. Kuznetsov // Korean Journal of Materials Research. - 2016. - № 26 (1). - P. 1-7.
27. Васильева, Ф.Д. Исследование свойств суспензии, пленок и бумаг оксида графита, синтезированного из природного графита месторождения Южной Якутии / Ф.Д. Васильева, А.Н. Капитонов, А.Е. Томская, С.А Смагулова // ЖСХ. - 2018. - № 59 (4). - P. 859
Review
For citations:
Egorova M.N., Tarasova L.A., Ahremenko Y.A., Ilarova V.I., Vasileva F.D., Smagulova S.A. ANTIMICROBIAL ACTIVITY OF GRAPHENE OXIDE. Vestnik of North-Eastern Federal University. Medical Sciences. 2019;(3):11-17. (In Russ.) https://doi.org/10.25587/SVFU.2019.3(16).39459
Views:
108
Email this article 