DYNAMICS OF CHANGES IN THE ACID-BASE STATUS PARAMETERS AS THE MAIN METHOD OF CONTROLLING TREATMENT OF BRONCHOPULMONARY DYSPLASIA: A CLINICAL CASE)

                The article describes a case of the development of a severe form of bronchopulmonary dysplasia in a premature newborn.

                Globally, about 15 million children are born prematurely every year. On average, it is every tenth child. In Russia, more than 110 thousand children are born prematurely every year, which is about 5.7 % of all newborns per year. [8] This confirms the relevance of the chosen topic.

                The ABS test falls under the category of express studies, since its parameters change rapidly with any shifts in the patient’s condition (respiratory indicators, body temperature, physical activity, kidney function, etc.). [9]

                The study of blood pH revealed subcompensated metabolic acidosis, confirming the literature data. The gas composition of the blood varied from hypocapnia to hypercapnia, which indicated a severe degree of respiratory failure with a picture of hypoventilation of the lungs in premature newborns. The revealed decrease in electrolytes was associated with diuretic and steroid therapy used for the patients with bronchopulmonary dysplasia. Due to prematurity, compensatory mechanisms were insufficient to maintain homeostatic parameters (pH, gas and electrolyte composition of blood).

                When conducting oxygen therapy with a ventilator, it is necessary to be guided by the dynamics of ABS tests to calibrate the parameters of the device and adjust infusion therapy.

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