The study used the SF-36 questionnaire, suitable for use in the general and clinical populations, to compare health status between populations and between diseases. In the world literature, data on the quality of life of the Evenks according to the SF-36 questionnaire were not found. The quality of life of the Evenks associated with the state of health has been studied. To conduct a survey of the adult population of the village of Zhilinda, a sample representative of gender and age was formed in the amount of 150 people, of which 69 were men (46 %) and 81 were women (54 %). The average age of the surveyed women was 43.3 ± 16.6 years, men - 41.1 ± 16.4 years. Gender comparisons were made. The questionnaire contained the following sections: general information, family income, living conditions, employment, nature of work, satisfaction with medical care and a medical examination card, consisting of sections: physical activity, smoking status, consumption of alcoholic beverages, Rose questionnaire, frequency of consumption of certain foods, quality of life questionnaire. To compare the quality of life of the inhabitants of the village of Zhilinda, the base of population values of the transformed indicators of the SF-36 questionnaire from the city of Yakutsk was used. The inhabitants of Zhilinda revealed low levels of physical functioning. The following factors were associated with decreased physical functioning: female gender, increased age, college education, increased body mass index, low income, and presence of joint/spine pain. Social functioning decreased with dissatisfaction with housing, vitality with low income, general health with an increase in the number of cigarettes smoked. Evenki quality of life can be significantly improved by reducing body weight, quitting smoking, treating diseases of the musculoskeletal system, increasing income and improving living conditions.